Italy works best as a road trip with 2–4 bases, not a new hotel every night. A car is great in Tuscany’s hill towns, Puglia, Sicily, Sardinia and the Dolomite passes — and a burden in Cinque Terre, the Amalfi Coast and Lake Como, where you park once and switch to trains, boats and buses. Every historic centre has a ZTL; rental cars don’t get permits automatically. Tolls are per km (about €0.08/km for a car on Autostrade in 2026) — calculate each leg. Km below are estimates unless marked official.
Checked 2026-09-23 · Italy · Itineraries
| At a glance | |
|---|---|
| Best with a car | Tuscany hills · Puglia · Sicily · Sardinia · Dolomites |
| Park once | Cinque Terre · Amalfi · Lake Como |
| Bases | 2–4, not nightly moves |
| Tolls | ~€0.08/km (car, Autostrade 2026) |
| ZTL | Every historic centre · no automatic permit |
Liguria, Tuscany and the lakes
R01 · Liguria + Cinque Terre
Parco Cinque Terre · Train MS Card ↗ · Autostrade · 2026 toll rates per km ↗
R02 · Tuscan coast: Castiglione to Carrara
Visit Tuscany · Tuscan coast itinerary (300 km) ↗ · Visit Tuscany · by car ↗
R03 · Tuscany hill towns
Visit Tuscany · by car ↗ · Comune di Siena · temporary ZTL permit ↗
R09 · Lake Como
R10 · Lake Garda
VisitGarda · by car ↗ · Navigazione Laghi · Lake Garda timetables ↗
R08 · Dolomites passes
The south and the islands
R04 · Amalfi and Sorrento
Visit Amalfi · getting around ↗ · Visit Amalfi · sustainable mobility lines ↗ · Travelmar · 2026 fares ↗
R05 · Puglia: Valle d’Itria + Salento
R06 · Sicily west to east
R07 · Sardinia: Gallura
Before you set off
ZTL on every leg
Calculating tolls
Rent for part of the trip
Quick answers
Which Italian regions are best for a road trip?
Tuscany’s hill towns, Puglia, Sicily, Sardinia and the Dolomite passes.
Should I drive the Amalfi Coast or Cinque Terre?
No — park once and use ferries, trains and buses.
How long is the Tuscan coast road trip?
The official Visit Tuscany route is 300 km, Castiglione della Pescaia to Marina di Carrara.
How are Italian motorway tolls calculated?
Per km by vehicle class — about €0.08/km for a car on Autostrade in 2026.
Go deeper in our guides
Related answers
Sources: Autostrade · 2026 toll rates per km ↗ · Visit Tuscany · Tuscan coast itinerary (300 km) ↗ · SardegnaTurismo · Gallura itinerary (99 km, 2 h 13) ↗ · Visit Sicily · Sicily by motorbike (SS113) ↗ · Val Gardena · Dolomites passes mobility ↗ · Visit Amalfi · getting around ↗ · Parco Cinque Terre · Train MS Card ↗